Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SUV39H2 | Q9H5I1 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SCD | O00767 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8866424 | 0.90 | ALDH1A1 (0.46) | SUV39H2KDM4EALDH1A1PTGS1PTGS2 | |
| SCHEMBL8867571 | 0.86 | ALDH1A1 (0.49) | KDM4EALDH1A1PTGS1PTGS2MEN1 | |
| SCHEMBL8866307 | 0.83 | SUV39H2 (0.46) | SUV39H2KDM4EALDH1A1TP53NPC1 | |
| SCHEMBL8866347 | 0.78 | RAB9A (0.46) | KDM4EALDH1A1PTGS1PTGS2MEN1 | |
| SCHEMBL8867143 | 0.76 | ALDH1A1 (0.41) | SUV39H2KDM4EALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL8866643 | 0.76 | SUV39H2 (0.47) | SUV39H2KDM4EALDH1A1KMT2ANPC1 | |
| SCHEMBL23220152 | 0.75 | PTGS1 (0.43) | SUV39H2KDM4EALDH1A1PTGS1PTGS2 | |
| SCHEMBL506934 | 0.74 | ANPEP (0.45) | ALDH1A1MEN1KMT2ATP53SMN1; SMN2 | |
| SCHEMBL8866329 | 0.72 | SUV39H2 (0.47) | SUV39H2KDM4EALDH1A1PTGS1PTGS2 | |
| SCHEMBL8867199 | 0.71 | ALDH1A1 (0.44) | SUV39H2KDM4EALDH1A1MEN1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614531-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-03-25 | — | — | US | disclosed |