Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.60 |
| ▸ | NPC1 | O15118 | 4/20 | 0.60 |
| ▸ | ALPL | P05186 | 1/20 | 0.56 |
| ▸ | ALPI | P09923 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | STAT1 | P42224 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | RET | P07949 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 1/20 | 0.50 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TNIK | Q9UKE5 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2320930 | 0.83 | APP (0.62) | RAB9ANPC1TNIK | |
| SCHEMBL2321798 | 0.83 | CDK1 (0.52) | RAB9ANPC1ALPLALPIMAPT | |
| SCHEMBL18366399 | 0.77 | RAB9A (0.57) | RAB9ANPC1ALPLALPIMAPT | |
| SCHEMBL22761277 | 0.77 | ALDH1A1 (0.61) | RAB9ANPC1ALPLALPIMAPT | |
| SCHEMBL2322234 | 0.76 | RAB9A (0.56) | RAB9ANPC1ALPLALPIMAPT | |
| SCHEMBL6562826 | 0.76 | NPC1 (1.00) | RAB9ANPC1ALPLALPIMAPT | |
| SCHEMBL13312208 | 0.75 | APP (0.70) | RAB9ANPC1ALPLALPIMAPT | |
| SCHEMBL18434151 | 0.75 | CHEK1 (0.67) | RAB9ANPC1ALPLALPIMAPT | |
| SCHEMBL1663611 | 0.73 | NPC1 (0.89) | RAB9ANPC1ALPLALPIMAPT | |
| SCHEMBL15362053 | 0.73 | RAB9A (0.55) | RAB9ANPC1ALPLALPIMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011094890-A1 | PHENYLALANINE DERIVATIVES AND THEIR USE AS NON-PEPTIDE GLP-1 RECEPTOR MODULATORS | ARGUSINA INC. (US) | 2011-08-11 | — | — | WO | disclosed |