Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PKLR | P30613 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SNCA | P37840 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.35 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18295943 | 0.84 | TSHR (0.47) | HSD17B10ALDH1A1KDM4EHPGDPKLR | |
| SCHEMBL8516332 | 0.81 | HSD17B10 (0.53) | HSD17B10ALDH1A1KDM4EHPGDPKLR | |
| SCHEMBL16502275 | 0.81 | TSHR (0.44) | HSD17B10ALDH1A1KDM4EHPGDTSHR | |
| SCHEMBL8516709 | 0.79 | ALDH1A1 (0.63) | HSD17B10ALDH1A1KDM4EHPGDPKLR | |
| SCHEMBL30422061 | 0.77 | ALDH1A1 (0.46) | HSD17B10ALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL2322069 | 0.77 | ALDH1A1 (0.46) | HSD17B10ALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL10154144 | 0.76 | TDP1 (0.37) | ALDH1A1KDM4ETSHRSMN1; SMN2SNCA | |
| SCHEMBL14639550 | 0.76 | SERPINE1 (0.39) | HSD17B10ALDH1A1KDM4EHPGDPKLR | |
| SCHEMBL8367520 | 0.76 | BACE1 (0.54) | HSD17B10ALDH1A1KDM4EHPGDPKLR | |
| SCHEMBL1120987 | 0.73 | CYP3A4 (0.58) | KDM4EGAATDP1ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899289-B1 | METHOD FOR PRODUCING ARYL AMINES, ARYL ETHERS AND ARYL THIOETHERS | ARCHIMICA GMBH (DE) | 2011-08-10 | — | — | EP | disclosed |
| US-20080306260-A1 | Method for Producing Aryl Amines, Aryl Ethers and Aryl Thioethers | ARCHIMICA GMBH (DE) | 2008-12-11 | — | — | US | disclosed |
| EP-1937613-A1 | PROCESS FOR PREPARING 2-ARYLCARBONYL COMPOUNDS, 2-ARYL ESTERS AND 2-ARYLNITRILES AND THEIR HETEROAROMATIC ANALOGUES | Archimica GmbH (DE) | 2008-07-02 | — | — | EP | disclosed |
| EP-1899289-A1 | METHOD FOR PRODUCING ARYL AMINES, ARYL ETHERS AND ARYL THIOETHERS | Archimica GmbH (DE) | 2008-03-19 | — | — | EP | disclosed |
| WO-2007033781-A1 | PROCESS FOR PREPARING 2-ARYLCARBONYL COMPOUNDS, 2-ARYL ESTERS AND 2-ARYLNITRILES AND THEIR HETEROAROMATIC ANALOGUES | ARCHIMICA GMBH (DE) | 2007-03-29 | — | — | WO | disclosed |
| WO-2007000250-A1 | METHOD FOR PRODUCING ARYL AMINES, ARYL ETHERS AND ARYL THIOETHERS | ARCHIMICA GMBH (DE) | 2007-01-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306260-A1 | Method for Producing Aryl Amines, Aryl Ethers and Aryl Thioethers | TST, TAAR1, TSHR | HSD17B10 2724/4885ALDH1A1 1524/4885KDM4E 3193/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.