Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 11/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.42 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 10/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 3/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23198044 | 0.79 | ADRB2 (0.62) | ADRB2CHRM3ADRB1 | |
| SCHEMBL18943485 | 0.79 | ADRB2 (0.62) | ADRB2CHRM3ADRB1 | |
| SCHEMBL23223712 | 0.72 | ADRB2 (0.42) | ADRB2CHRM3ADRB1DRD2ADRA1D | |
| SCHEMBL18943231 | 0.70 | EPHX1 (0.39) | CXCR5NPC1USP2RAB9ASMN1; SMN2 | |
| SCHEMBL23223710 | 0.68 | CHRM3 (0.73) | ADRB2CHRM3 | |
| SCHEMBL23223746 | 0.68 | ADRB2 (0.68) | ADRB2CHRM3ADRB1 | |
| SCHEMBL20373416 | 0.67 | ADRB2 (0.40) | ADRB2ADRB1DRD2 | |
| SCHEMBL18918491 | 0.67 | ADRB2 (0.66) | ADRB2CHRM3 | |
| SCHEMBL23198076 | 0.67 | ADRB2 (0.66) | ADRB2CHRM3 | |
| SCHEMBL23198121 | 0.67 | ADRB2 (0.74) | ADRB2CHRM3ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3383867-B1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARM SPA (IT) | 2021-04-14 | — | — | EP | disclosed |