Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 20/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 19/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20373657 | 0.82 | ADRB2 (0.40) | ADRB2ADRB1DRD2DRD3 | |
| SCHEMBL21573556 | 0.77 | ADRB2 (0.41) | ADRB2ADRB1DRD2DRD3 | |
| SCHEMBL21573521 | 0.74 | KDM4E (0.37) | ADRB2ADRB1DRD2 | |
| SCHEMBL20373403 | 0.70 | ADRB2 (0.74) | ADRB2ADRB1 | |
| SCHEMBL21573495 | 0.70 | ADRB2 (0.42) | ADRB2ADRB1DRD2 | |
| SCHEMBL18946397 | 0.69 | ADRB1 (0.43) | ADRB2ADRB1DRD2DRD3 | |
| SCHEMBL14036266 | 0.68 | KDM4E (0.47) | ADRB2ADRB1DRD2 | |
| SCHEMBL23223708 | 0.67 | ADRB2 (0.42) | ADRB2ADRB1DRD2 | |
| SCHEMBL23223709 | 0.66 | ADRB2 (0.39) | ADRB2ADRB1 | |
| SCHEMBL21573538 | 0.61 | ADRB2 (0.43) | ADRB2ADRB1DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3345904-A1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | Chiesi Farmaceutici S.p.a. (IT) | 2018-07-11 | — | — | EP | disclosed |