Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | TP53BP1 | Q12888 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CASR | P41180 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18918531 | 0.93 | SMN1; SMN2 (0.56) | SMN1; SMN2EPHX1ATMGAAMAPT | |
| SCHEMBL18918566 | 0.82 | SMN1; SMN2 (0.57) | SMN1; SMN2EPHX1ATMGAAMAPT | |
| SCHEMBL18259868 | 0.80 | POLB (0.61) | SMN1; SMN2EPHX1MAPTPOLBL3MBTL1 | |
| SCHEMBL9313118 | 0.79 | SMN1; SMN2 (0.62) | SMN1; SMN2GAAMAPTPAX8TP53BP1 | |
| SCHEMBL10793568 | 0.79 | SMN1; SMN2 (0.82) | SMN1; SMN2GAAMAPTPOLBKDM5B | |
| SCHEMBL19943110 | 0.78 | SMN1; SMN2 (0.74) | SMN1; SMN2GAAMAPTPOLBKDM5B | |
| SCHEMBL18918544 | 0.77 | SMN1; SMN2 (0.50) | SMN1; SMN2EPHX1ATMGAAMAPT | |
| SCHEMBL23223763 | 0.76 | SMN1; SMN2 (0.47) | SMN1; SMN2EPHX1ATMGAAMAPT | |
| SCHEMBL29798859 | 0.76 | NPC1 (0.58) | SMN1; SMN2EPHX1POLBL3MBTL1KMT2A | |
| SCHEMBL10790383 | 0.76 | L3MBTL1 (0.67) | SMN1; SMN2GAAMAPTPOLBKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3383867-B1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARM SPA (IT) | 2021-04-14 | — | — | EP | disclosed |