Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | TP53BP1 | Q12888 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | NAAA | Q02083 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9313528 | 0.87 | ALDH1A1 (0.64) | SMN1; SMN2ALDH1A1L3MBTL1NAAA | |
| SCHEMBL18918531 | 0.83 | SMN1; SMN2 (0.56) | SMN1; SMN2KMT2AGAAHSD17B10MAPT | |
| SCHEMBL16213688 | 0.81 | ALDH1A1 (0.53) | SMN1; SMN2TDP1ALDH1A1L3MBTL1 | |
| SCHEMBL18918566 | 0.81 | SMN1; SMN2 (0.57) | SMN1; SMN2KMT2AGAAHSD17B10MAPT | |
| SCHEMBL9312206 | 0.81 | KMT2A (0.67) | SMN1; SMN2KMT2AGAAHSD17B10MAPT | |
| SCHEMBL23223763 | 0.80 | SMN1; SMN2 (0.47) | SMN1; SMN2KMT2AGAAMAPTMEN1 | |
| SCHEMBL16213694 | 0.79 | ALDH1A1 (0.54) | SMN1; SMN2TDP1ALDH1A1L3MBTL1 | |
| SCHEMBL23223972 | 0.79 | SMN1; SMN2 (0.51) | SMN1; SMN2KMT2AGAAHSD17B10MAPT | |
| SCHEMBL10137830 | 0.78 | SMN1; SMN2 (0.60) | SMN1; SMN2KMT2AGAAHSD17B10MAPT | |
| SCHEMBL16117373 | 0.77 | SMN1; SMN2 (1.00) | SMN1; SMN2KMT2AGAAHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5360876-A | Formaldehyde-free | BURGOYNE JR WILLIAM F (US) | 1994-11-01 | — | — | US | claimed |
| US-5360876-A | Formaldehyde-free | BURGOYNE JR WILLIAM F (US) | 1994-11-01 | — | — | US | disclosed |
| US-5336807-A | Diurea-,-carbamate- or -amide-containing acetal compounds; stable as solids or liquids; replace formaldehyde-containing resin crosslinkers in adhesives and coatings | AIR PRODUCTS & CHEMICALS, INC. (US) | 1994-08-09 | — | — | US | disclosed |