Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPY1R | P25929 | 1/20 | 0.42 |
| ▸ | NPY2R | P49146 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19784363 | 0.79 | CDK4 (0.48) | KMT2AMEN1MAPTSMN1; SMN2HTR1A | |
| SCHEMBL2892762 | 0.69 | MEN1 (0.89) | KMT2AMEN1MAPTALDH1A1TAAR1 | |
| SCHEMBL7840693 | 0.68 | KDM4E (0.57) | KMT2AMEN1ALDH1A1TAAR1SMN1; SMN2 | |
| Bromide SCHEMBL11670771 | 0.67 | KDM4E (0.56) | KMT2AMEN1ALDH1A1TAAR1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11669913 | 0.67 | KDM4E (0.56) | KMT2AMEN1ALDH1A1TAAR1SMN1; SMN2 | |
| SCHEMBL24404482 | 0.67 | HDAC1 (0.38) | ALDH1A1KDM4EBCHECCNB2CDK1 | |
| SCHEMBL23223711 | 0.67 | HTR2A (0.38) | HTR2ACA12CA1CA2CA4 | |
| SCHEMBL4859909 | 0.65 | MEN1 (0.64) | KMT2AMEN1MAPTALDH1A1TAAR1 | |
| SCHEMBL15509301 | 0.65 | MAPT (1.00) | KMT2AMEN1MAPTALDH1A1CYP19A1 | |
| SCHEMBL1041853 | 0.65 | MEN1 (0.69) | KMT2AMEN1MAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3383867-B1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARM SPA (IT) | 2021-04-14 | — | — | EP | disclosed |