Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SQOR | Q9Y6N5 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.50 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TK1 | P04183 | 1/20 | 0.37 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.37 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.37 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20334523 | 0.84 | CYP2C19 (0.51) | SQORCYP2C19ALDH1A1GAATDP1 | |
| SCHEMBL20334744 | 0.84 | CYP2C19 (0.51) | SQORCYP2C19ALDH1A1GAATDP1 | |
| SCHEMBL22106705 | 0.84 | CYP2C19 (0.51) | SQORCYP2C19ALDH1A1GAATDP1 | |
| SCHEMBL23353346 | 0.84 | CYP2C19 (0.51) | SQORCYP2C19ALDH1A1GAATDP1 | |
| SCHEMBL20820202 | 0.82 | SMN1; SMN2 (0.59) | SQORCYP2C19ASAH1ALDH1A1GAA | |
| SCHEMBL21275595 | 0.80 | CYP2C19 (0.51) | SQORCYP2C19ALDH1A1GAATDP1 | |
| SCHEMBL20870852 | 0.80 | CYP2C19 (0.48) | SQORCYP2C19ASAH1ALDH1A1GAA | |
| SCHEMBL23278563 | 0.80 | CYP2C19 (0.45) | SQORCYP2C19ASAH1ALDH1A1GAA | |
| SCHEMBL20870271 | 0.78 | CYP2C19 (0.46) | SQORCYP2C19ASAH1ALDH1A1GAA | |
| SCHEMBL20870270 | 0.78 | CYP2C19 (0.46) | SQORCYP2C19ASAH1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210106604-A1 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF | Janssen Pharmaceuticals, Inc. | 2021-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210106604-A1 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF | PNP, NUDT1, NT5C3B | SQOR 3743/4885CYP2C19 3335/4885ASAH1 533/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.