Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | MPO | P05164 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23225699 | 0.81 | OPRM1 (0.39) | OPRM1MPO | |
| SCHEMBL29879452 | 0.80 | OPRM1 (0.37) | OPRM1MPO | |
| SCHEMBL28849738 | 0.78 | OPRM1 (0.37) | OPRM1MPO | |
| SCHEMBL29879210 | 0.78 | OPRM1 (0.37) | OPRM1MPO | |
| SCHEMBL28957065 | 0.73 | OPRM1 (0.33) | OPRM1MPO | |
| SCHEMBL23225608 | 0.72 | OPRM1 (0.40) | OPRM1MPO | |
| SCHEMBL23225606 | 0.65 | OPRM1 (0.36) | OPRM1MPO | |
| SCHEMBL29211274 | 0.63 | OPRM1 (0.31) | OPRM1MPO | |
| SCHEMBL29211243 | 0.62 | HSP90AA1 (0.32) | OPRM1MPOHSP90AA1 | |
| SCHEMBL29211266 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021072140-A1 | PRODRUGS OF MYELOPEROXIDASE INHIBITORS | BIOHAVEN THERAPEUTICS LTD. (US) | 2021-04-15 | — | — | WO | disclosed |