Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | MPO | P05164 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23225609 | 0.81 | OPRM1 (0.37) | OPRM1MPO | |
| SCHEMBL29879452 | 0.81 | OPRM1 (0.37) | OPRM1MPO | |
| SCHEMBL28849738 | 0.81 | OPRM1 (0.37) | OPRM1MPO | |
| SCHEMBL29879210 | 0.81 | OPRM1 (0.37) | OPRM1MPO | |
| SCHEMBL29211266 | 0.80 | — | — | |
| SCHEMBL29211243 | 0.79 | HSP90AA1 (0.32) | OPRM1MPO | |
| SCHEMBL23225608 | 0.78 | OPRM1 (0.40) | OPRM1MPO | |
| SCHEMBL29211274 | 0.78 | OPRM1 (0.31) | OPRM1MPO | |
| SCHEMBL29211252 | 0.77 | OPRM1 (0.31) | OPRM1MPO | |
| SCHEMBL28957065 | 0.76 | OPRM1 (0.33) | OPRM1MPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240067651-A1 | PRODRUGS OF MYELOPEROXIDASE INHIBITORS | BIOHAVEN THERAPEUTICS LTD. | 2024-02-29 | — | — | US | disclosed |
| CN-110891572-B | MPO inhibitors for medical use | 阿斯利康(瑞典)有限公司 | 2023-08-15 | — | — | CN | disclosed |
| WO-2021072140-A1 | PRODRUGS OF MYELOPEROXIDASE INHIBITORS | BIOHAVEN THERAPEUTICS LTD. (US) | 2021-04-15 | — | — | WO | disclosed |
| CN-110891572-A | MPO inhibitors for use in medicine | 阿斯利康(瑞典)有限公司 | 2020-03-17 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240067651-A1 | PRODRUGS OF MYELOPEROXIDASE INHIBITORS | MPO, CAT, SOD1 | OPRM1 1161/4885MPO 1/4885HPGD 137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.