Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | MPO | P05164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23217963 | 0.93 | POLB (0.38) | POLBGAANPSR1OPRM1MPO | |
| SCHEMBL23218019 | 0.83 | OPRM1 (0.32) | OPRM1MPO | |
| SCHEMBL23225679 | 0.80 | — | — | |
| SCHEMBL23225604 | 0.79 | MPO (0.35) | OPRM1MPO | |
| SCHEMBL27103673 | 0.79 | — | — | |
| SCHEMBL27103572 | 0.78 | OPRM1 (0.32) | OPRM1MPO | |
| SCHEMBL27144508 | 0.76 | — | — | |
| SCHEMBL27102076 | 0.75 | KDM4E (0.31) | GAA | |
| SCHEMBL23225722 | 0.74 | OPRM1 (0.32) | OPRM1MPO | |
| SCHEMBL23225599 | 0.74 | MPO (0.54) | GAAOPRM1MPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021072140-A1 | PRODRUGS OF MYELOPEROXIDASE INHIBITORS | BIOHAVEN THERAPEUTICS LTD. (US) | 2021-04-15 | — | — | WO | disclosed |