SCHEMBL2322596

SCHEMBL2322596

CCCCCCCCCCCCCCCCCCOC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HLCS P50747 6/20 0.71
TDP1 Q9NUW8 6/20 0.69
MEN1 O00255 1/20 0.61
ABL1 P00519 1/20 0.61
LMNA P02545 1/20 0.61
PKM P14618 1/20 0.61
IDE P14735 1/20 0.61
MAPK1 P28482 1/20 0.61
KMT2A Q03164 1/20 0.61
RIN1 Q13671 1/20 0.61
L3MBTL1 Q9Y468 1/20 0.61
HPSE Q9Y251 1/20 0.57
CNR1 P21554 3/20 0.57
CNR2 P34972 2/20 0.57
F2 P00734 1/20 0.50
PRSS1 P07477 1/20 0.50
PRSS2 P07478 1/20 0.50
PRSS3 P35030 1/20 0.50
TPSAB1 Q15661 1/20 0.50
PLCD1 P51178 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10389671 1.00 HLCS (0.71) HLCSTDP1MEN1ABL1LMNA
SCHEMBL7267179 1.00 HLCS (0.71) HLCSTDP1MEN1ABL1LMNA
SCHEMBL9912047 0.95 TDP1 (0.72) HLCSTDP1MEN1ABL1LMNA
SCHEMBL10854680 0.95 TDP1 (0.72) HLCSTDP1MEN1ABL1LMNA
SCHEMBL10124218 0.92 TDP1 (0.74) HLCSTDP1MEN1ABL1LMNA
SCHEMBL10854861 0.92 TDP1 (0.74) HLCSTDP1MEN1ABL1LMNA
SCHEMBL20711427 0.91 HLCS (0.59) HLCSTDP1MEN1ABL1LMNA
SCHEMBL7157942 0.90 TDP1 (0.77) HLCSTDP1MEN1ABL1LMNA
SCHEMBL18944226 0.89 HLCS (0.59) HLCSTDP1MEN1ABL1LMNA
SCHEMBL4474965 0.89 TDP1 (0.66) HLCSTDP1MEN1ABL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102307885-B Method for introducing functional groups to the surface of a substance NAT UNIV KANGNUNG WONJU 2015-04-29 CN claimed
CN-102307885-A Method for introducing functional groups to the surface of a substance NAT UNIV KANGNUNG WONJU 2012-01-04 CN claimed
US-20110223318-A1 METHOD FOR INTRODUCING FUNCTIONAL GROUP TO SURFACE OF MATERIAL KANGNUNG-WONJU NATIONAL UNIVERSITY INDUSTRY ACADEMY COOPERATION GROUP (KR) 2011-09-15 US claimed
EP-2354146-A1 METHOD FOR INTRODUCING FUNCTIONAL GROUP TO SURFACE OF MATERIAL Kangnung-Wonju National University Industry Academy Cooperation Group (KR) 2011-08-10 EP claimed
CN-102307885-B Method for introducing functional groups to the surface of a substance NAT UNIV KANGNUNG WONJU 2015-04-29 CN disclosed
CN-102307885-A Method for introducing functional groups to the surface of a substance NAT UNIV KANGNUNG WONJU 2012-01-04 CN disclosed
US-20110223318-A1 METHOD FOR INTRODUCING FUNCTIONAL GROUP TO SURFACE OF MATERIAL KANGNUNG-WONJU NATIONAL UNIVERSITY INDUSTRY ACADEMY COOPERATION GROUP (KR) 2011-09-15 US disclosed
EP-2354146-A1 METHOD FOR INTRODUCING FUNCTIONAL GROUP TO SURFACE OF MATERIAL Kangnung-Wonju National University Industry Academy Cooperation Group (KR) 2011-08-10 EP disclosed
WO-2010044523-A1 METHOD FOR INTRODUCING FUNCTIONAL GROUP TO SURFACE OF MATERIAL 강릉원주대학교산학협력단 (KR) 2010-04-22 WO disclosed
US-7368280-B2 Detection of biospecific interactions using amplified differential time domain spectroscopy signal RENSSELAER POLYTECHNIC INSTITUTE (US) 2008-05-06 US disclosed
US-20060045807-A1 Detection of biospecific interactions using amplified differential time domain spectroscopy signal RENSSELAER POLYTECHNIC INSTITUTE 2006-03-02 US disclosed
WO-2003100396-A1 DETECTION OF BIOSPECIFIC INTERACTIONS USING AMPLIFIED DIFFERENTIAL TIME DOMAIN SPECTROSCOPY SIGNAL RENSSELAER POLYTECHNIC INSTITUTE (US) 2003-12-04 WO disclosed