Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.72 |
| ▸ | HLCS | P50747 | 6/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | ABL1 | P00519 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.64 |
| ▸ | IDE | P14735 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.59 |
| ▸ | CNR1 | P21554 | 3/20 | 0.53 |
| ▸ | CNR2 | P34972 | 2/20 | 0.53 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.49 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10854680 | 1.00 | TDP1 (0.72) | TDP1HLCSMEN1ABL1LMNA | |
| SCHEMBL7267179 | 0.95 | HLCS (0.71) | TDP1HLCSMEN1ABL1LMNA | |
| SCHEMBL2322596 | 0.95 | HLCS (0.71) | TDP1HLCSMEN1ABL1LMNA | |
| SCHEMBL10389671 | 0.95 | HLCS (0.71) | TDP1HLCSMEN1ABL1LMNA | |
| SCHEMBL10124218 | 0.94 | TDP1 (0.74) | TDP1HLCSMEN1ABL1LMNA | |
| SCHEMBL10854861 | 0.94 | TDP1 (0.74) | TDP1HLCSMEN1ABL1LMNA | |
| SCHEMBL7157942 | 0.92 | TDP1 (0.77) | TDP1HLCSMEN1ABL1LMNA | |
| SCHEMBL12050324 | 0.89 | TDP1 (0.77) | TDP1HLCSMEN1ABL1LMNA | |
| SCHEMBL1934693 | 0.89 | TDP1 (0.77) | TDP1HLCSMEN1ABL1LMNA | |
| SCHEMBL3789590 | 0.88 | TDP1 (0.69) | TDP1HLCSMEN1ABL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8198099-B2 | Mechanism to signal receptor-ligand interactions with luminescent quantum dots | THE UNIVERSITY OF MIAMI (US) | 2012-06-12 | — | — | US | disclosed |
| US-20100112560-A1 | MECHANISM TO SIGNAL RECEPTOR-LIGAND INTERACTIONS WITH LUMINESCENT QUANTUM DOTS | UNIVERSITY OF MIAMI, THE | 2010-05-06 | — | — | US | disclosed |