Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 19/20 | 0.59 |
| ▸ | DDB1 | Q16531 | 15/20 | 0.59 |
| ▸ | IKZF3 | Q9UKT9 | 4/20 | 0.59 |
| ▸ | TNF | P01375 | 3/20 | 0.59 |
| ▸ | IL1B | P01584 | 3/20 | 0.59 |
| ▸ | IKZF1 | Q13422 | 2/20 | 0.59 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.59 |
| ▸ | BRD4 | O60885 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1907861 | 0.86 | CRBN (0.60) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL23565015 | 0.86 | CRBN (0.53) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL20612264 | 0.85 | CRBN (0.59) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL23226107 | 0.85 | CRBN (0.58) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL30938886 | 0.83 | CRBN (0.50) | CRBNDDB1IKZF3TNFIL1B | |
| Hydrochloric Acid SCHEMBL5138324 | 0.83 | CRBN (0.54) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL23225995 | 0.81 | HTR2B (0.39) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL19771065 | 0.80 | CRBN (0.61) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL22873882 | 0.79 | CRBN (0.51) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL30938932 | 0.78 | CRBN (0.66) | CRBNDDB1IKZF3TNFIL1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021068380-A1 | PREPARATION OF DEGRADATION COMPOUND TARGETING BTK PROTEIN, AND APPLICATION THEREOF IN TREATING AUTOIMMUNE DISEASES AND TUMORS | 清华大学 | 2021-04-15 | — | — | WO | disclosed |