Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TMPRSS4 | Q9NRS4 | 3/20 | 0.41 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.41 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.41 |
| ▸ | IL2 | P60568 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | SMO | Q99835 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23226470 | 0.93 | MEN1 (0.45) | MEN1KMT2ACYP3A4CYP2D6CYP2C19 | |
| SCHEMBL23226420 | 0.90 | MEN1 (0.43) | MEN1KMT2ACYP3A4CYP2D6CYP2C19 | |
| SCHEMBL23226758 | 0.89 | TRPV1 (0.39) | MEN1KMT2ACYP3A4CYP2D6CYP2C19 | |
| SCHEMBL23226443 | 0.85 | KMT2A (0.49) | MEN1KMT2ACYP3A4CYP2D6CYP2C19 | |
| SCHEMBL23226416 | 0.84 | STING1 (0.45) | MEN1KMT2ALMNATMPRSS4P2RX1 | |
| SCHEMBL23226430 | 0.83 | STING1 (0.46) | MEN1KMT2ACYP3A4CYP2D6CYP2C19 | |
| SCHEMBL23226444 | 0.83 | MEN1 (0.60) | MEN1KMT2ACYP3A4CYP2D6CYP2C19 | |
| SCHEMBL30116622 | 0.83 | ALDH1A1 (0.50) | MEN1KMT2ACYP3A4CYP2D6CYP2C19 | |
| SCHEMBL30116638 | 0.82 | MEN1 (0.46) | MEN1KMT2ACYP3A4CYP2D6CYP2C19 | |
| SCHEMBL23226421 | 0.81 | STING1 (0.47) | MEN1KMT2ACYP3A4CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021068950-A1 | AMIDE COMPOUND AND MEDICAL USE THEREOF AS STING INHIBITOR | 中国药科大学 | 2021-04-15 | — | — | WO | disclosed |