Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | GCGR | P47871 | 5/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.42 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.42 |
| ▸ | IL2 | P60568 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23226443 | 0.92 | KMT2A (0.49) | MEN1KMT2ACYP3A4CYP2D6CYP2C19 | |
| SCHEMBL30116622 | 0.88 | ALDH1A1 (0.50) | MEN1KMT2ACYP3A4CYP2D6CYP2C19 | |
| SCHEMBL30116638 | 0.85 | MEN1 (0.46) | MEN1KMT2ACYP3A4CYP2D6CYP2C19 | |
| SCHEMBL23226430 | 0.85 | STING1 (0.46) | MEN1KMT2ACYP3A4CYP2D6CYP2C19 | |
| SCHEMBL23226475 | 0.84 | MEN1 (0.46) | MEN1KMT2ACYP3A4CYP2D6CYP2C19 | |
| SCHEMBL23226470 | 0.84 | MEN1 (0.45) | MEN1KMT2ACYP3A4CYP2D6CYP2C19 | |
| SCHEMBL23226429 | 0.83 | MEN1 (0.44) | MEN1KMT2ACYP3A4CYP2D6CYP2C19 | |
| SCHEMBL23226421 | 0.83 | STING1 (0.47) | MEN1KMT2ACYP3A4CYP2D6CYP2C19 | |
| SCHEMBL23226420 | 0.82 | MEN1 (0.43) | MEN1KMT2ACYP3A4CYP2D6CYP2C19 | |
| SCHEMBL23226844 | 0.82 | P2RX1 (0.48) | MEN1KMT2ACYP3A4CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021068950-A1 | AMIDE COMPOUND AND MEDICAL USE THEREOF AS STING INHIBITOR | 中国药科大学 | 2021-04-15 | — | — | WO | disclosed |