Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | MGLL | Q99685 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.51 |
| ▸ | GLA | P06280 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | PRKDC | P78527 | 2/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23226763 | 0.83 | NPC1 (0.59) | ALDH1A1HSD17B10ALOX15HPGDMGLL | |
| SCHEMBL2773168 | 0.82 | KMT2A (0.57) | ALDH1A1HSD17B10ALOX15HPGDMGLL | |
| SCHEMBL7435442 | 0.81 | KDM4E (0.75) | ALDH1A1HSD17B10ALOX15HPGDMGLL | |
| SCHEMBL16869527 | 0.81 | KMT2A (0.58) | ALDH1A1HSD17B10ALOX15HPGDMGLL | |
| SCHEMBL6597425 | 0.81 | ALDH1A1 (0.56) | ALDH1A1HSD17B10ALOX15HPGDMGLL | |
| SCHEMBL2771499 | 0.80 | SMN1; SMN2 (0.62) | ALDH1A1HSD17B10ALOX15HPGDMGLL | |
| SCHEMBL24266512 | 0.79 | NPC1 (0.61) | ALDH1A1HSD17B10ALOX15HPGDMGLL | |
| SCHEMBL4906777 | 0.77 | SMN1; SMN2 (0.54) | ALDH1A1HSD17B10ALOX15HPGDMGLL | |
| SCHEMBL1063179 | 0.77 | ALDH1A1 (0.67) | ALDH1A1HSD17B10ALOX15HPGDMGLL | |
| SCHEMBL7428427 | 0.76 | MAPT (0.72) | ALDH1A1HPGDKMT2ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021068950-A1 | AMIDE COMPOUND AND MEDICAL USE THEREOF AS STING INHIBITOR | 中国药科大学 | 2021-04-15 | — | — | WO | disclosed |