Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.50 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | VCP | P55072 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27833127 | 0.79 | GBA1 (0.56) | GBA1AOC3DGAT1MEN1KMT2A | |
| SCHEMBL2322685 | 0.77 | GBA1 (0.50) | GBA1AOC3DGAT1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL11157402 | 0.76 | GBA1 (0.53) | GBA1AOC3DGAT1MEN1KMT2A | |
| SCHEMBL224555 | 0.74 | MAPT (0.55) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL10622006 | 0.72 | GBA1 (0.62) | GBA1AOC3MEN1KMT2AALDH1A1 | |
| SCHEMBL179288 | 0.72 | GBA1 (0.62) | GBA1AOC3KMT2AHCAR3KDM4E | |
| SCHEMBL21628214 | 0.71 | GBA1 (0.47) | GBA1AOC3DGAT1MEN1KMT2A | |
| SCHEMBL29636439 | 0.71 | GBA1 (0.47) | GBA1AOC3DGAT1MEN1KMT2A | |
| SCHEMBL3054038 | 0.71 | AURKA (0.54) | GBA1AOC3MEN1KMT2AALDH1A1 | |
| SCHEMBL17274025 | 0.71 | GBA1 (0.60) | GBA1AOC3KMT2AALDH1A1HCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011094890-A1 | PHENYLALANINE DERIVATIVES AND THEIR USE AS NON-PEPTIDE GLP-1 RECEPTOR MODULATORS | ARGUSINA INC. (US) | 2011-08-11 | — | — | WO | disclosed |