Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.50 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.36 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.34 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.34 |
| ▸ | MYC | P01106 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5710510 | 0.81 | KDM1A (0.45) | LMNATRPV1ALDH1A1KDM1A | |
| SCHEMBL27833127 | 0.79 | GBA1 (0.56) | GBA1AOC3LMNADGAT1TRPV1 | |
| SCHEMBL28161952 | 0.77 | LMNA (0.40) | LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL2322679 | 0.77 | GBA1 (0.50) | GBA1AOC3LMNADGAT1TRPV1 | |
| Hydrochloric Acid SCHEMBL11157402 | 0.76 | GBA1 (0.53) | GBA1AOC3LMNADGAT1HCAR3 | |
| SCHEMBL30369918 | 0.75 | ALDH1A1 (0.57) | GBA1AOC3LMNAHCAR3ALDH1A1 | |
| SCHEMBL19330155 | 0.75 | ALDH1A1 (0.57) | GBA1AOC3LMNAHCAR3ALDH1A1 | |
| SCHEMBL29636439 | 0.74 | GBA1 (0.47) | GBA1AOC3DGAT1TRPV1HCAR3 | |
| SCHEMBL21628214 | 0.74 | GBA1 (0.47) | GBA1AOC3DGAT1TRPV1HCAR3 | |
| SCHEMBL224556 | 0.73 | ALDH1A1 (0.59) | LMNAALDH1A1ALDH3A1ALDH1A3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011094890-A1 | PHENYLALANINE DERIVATIVES AND THEIR USE AS NON-PEPTIDE GLP-1 RECEPTOR MODULATORS | ARGUSINA INC. (US) | 2011-08-11 | — | — | WO | disclosed |