Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.50 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.50 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | RXRA | P19793 | 2/20 | 0.50 |
| ▸ | RXRB | P28702 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.50 |
| ▸ | RXRG | P48443 | 1/20 | 0.50 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.48 |
| ▸ | XBP1 | P17861 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23226848 | 0.83 | APP (0.48) | HDAC3HDAC8HDAC6TRPV1P2RX1 | |
| SCHEMBL171136 | 0.83 | P2RX1 (0.63) | HDAC3HDAC8HDAC6P2RX1MAPT | |
| SCHEMBL24628415 | 0.83 | DEGS1 (0.60) | HDAC6MAPTMEN1NPC1RAB9A | |
| SCHEMBL23226844 | 0.82 | P2RX1 (0.48) | TRPV1P2RX1MAPTMEN1NPC1 | |
| SCHEMBL23226828 | 0.81 | TRPV1 (0.55) | TRPV1P2RX1NPC1LMNARAB9A | |
| SCHEMBL23226585 | 0.81 | KMT2A (0.64) | TRPV1MAPTMEN1NPC1LMNA | |
| SCHEMBL23226833 | 0.80 | TRPV1 (0.49) | TRPV1MAPTMEN1NPC1LMNA | |
| SCHEMBL1264161 | 0.80 | MEN1 (0.70) | TRPV1P2RX1MAPTMEN1LMNA | |
| SCHEMBL30116608 | 0.75 | STING1 (0.76) | HDAC3HDAC8HDAC6P2RX1MAPT | |
| SCHEMBL10242069 | 0.75 | KMT2A (0.71) | MAPTMEN1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021068950-A1 | AMIDE COMPOUND AND MEDICAL USE THEREOF AS STING INHIBITOR | 中国药科大学 | 2021-04-15 | — | — | WO | disclosed |