Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 2/20 | 0.48 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.48 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.48 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.48 |
| ▸ | IL2 | P60568 | 1/20 | 0.47 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.45 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.45 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.45 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23226848 | 0.88 | APP (0.48) | P2RX1P2RX4P2RX7TMPRSS4IL2 | |
| SCHEMBL23226443 | 0.83 | KMT2A (0.49) | P2RX1P2RX4P2RX7TMPRSS4IL2 | |
| SCHEMBL23226421 | 0.83 | STING1 (0.47) | P2RX1P2RX4P2RX7TMPRSS4IL2 | |
| SCHEMBL23226420 | 0.83 | MEN1 (0.43) | P2RX1P2RX4P2RX7TMPRSS4IL2 | |
| SCHEMBL23226814 | 0.82 | HDAC3 (0.53) | P2RX1TMPRSS4TRPV1MEN1KMT2A | |
| SCHEMBL23226438 | 0.82 | STING1 (0.48) | P2RX1P2RX4P2RX7TMPRSS4IL2 | |
| SCHEMBL23226444 | 0.82 | MEN1 (0.60) | P2RX1P2RX4P2RX7TMPRSS4IL2 | |
| SCHEMBL23226430 | 0.82 | STING1 (0.46) | P2RX1P2RX4P2RX7TMPRSS4IL2 | |
| SCHEMBL23226707 | 0.81 | STING1 (0.47) | P2RX1P2RX4P2RX7TMPRSS4IL2 | |
| SCHEMBL30116622 | 0.81 | ALDH1A1 (0.50) | P2RX1P2RX4P2RX7TMPRSS4IL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021068950-A1 | AMIDE COMPOUND AND MEDICAL USE THEREOF AS STING INHIBITOR | 中国药科大学 | 2021-04-15 | — | — | WO | disclosed |