Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DEGS1 | O15121 | 1/20 | 0.60 |
| ▸ | SNCA | P37840 | 2/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.56 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.56 |
| ▸ | NQO2 | P16083 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | TOP1 | P11387 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | RAF1 | P04049 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | BRAF | P15056 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23226585 | 0.90 | KMT2A (0.64) | DEGS1HSP90AA1HSP90AB1NPC1RAB9A | |
| SCHEMBL10242069 | 0.83 | KMT2A (0.71) | HSP90AA1HSP90AB1NPC1RAB9AKMT2A | |
| SCHEMBL12937374 | 0.83 | TOP1 (0.74) | SNCAHSP90AA1HSP90AB1NPC1RAB9A | |
| SCHEMBL23226814 | 0.83 | HDAC3 (0.53) | SNCAHSP90AA1HSP90AB1NPC1RAB9A | |
| SCHEMBL26815735 | 0.82 | NPC1 (0.59) | DEGS1SNCANQO2NPC1RAB9A | |
| SCHEMBL24628629 | 0.82 | SNCA (0.60) | DEGS1SNCANQO2NPC1RAB9A | |
| SCHEMBL20284045 | 0.82 | DEGS1 (0.86) | DEGS1SNCANQO2NPC1RAB9A | |
| SCHEMBL20284419 | 0.81 | NPC1 (0.76) | DEGS1SNCANQO2NPC1RAB9A | |
| SCHEMBL6781288 | 0.79 | DEGS1 (0.69) | DEGS1NPC1RAB9AKMT2ATP53 | |
| SCHEMBL24628602 | 0.79 | MEN1 (0.67) | DEGS1NPC1RAB9AKMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4276092-A1 | COMPOUND LIBRARY | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2023-11-15 | — | — | EP | disclosed |
| WO-2022149617-A1 | COMPOUND LIBRARY | 中外製薬株式会社 | 2022-07-14 | — | — | WO | disclosed |