Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 7/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | F11 | P03951 | 5/20 | 0.43 |
| ▸ | TPSB2 | P20231 | 4/20 | 0.43 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.43 |
| ▸ | PLG | P00747 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | F7 | P08709 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23218858 | 0.93 | CFD (0.54) | CFDFFAR1GAAMEN1POLB | |
| SCHEMBL29853271 | 0.93 | CFD (0.54) | CFDFFAR1GAAMEN1POLB | |
| SCHEMBL23229127 | 0.91 | MAPT (0.48) | CFDGAAMEN1POLBKMT2A | |
| SCHEMBL23229126 | 0.90 | CFD (0.55) | CFDFFAR1F11TPSB2KLKB1 | |
| SCHEMBL29853224 | 0.85 | CFD (0.54) | CFDFFAR1F11TPSB2KLKB1 | |
| SCHEMBL23218760 | 0.85 | CFD (0.54) | CFDFFAR1F11TPSB2KLKB1 | |
| SCHEMBL23229139 | 0.84 | GAA (0.58) | GAAMEN1POLBKMT2AMAPT | |
| SCHEMBL23218888 | 0.84 | CFD (0.47) | CFDFFAR1F11TPSB2KLKB1 | |
| SCHEMBL23229138 | 0.83 | POLB (0.49) | CFDGAAMEN1POLBKMT2A | |
| SCHEMBL23229195 | 0.83 | CFD (0.42) | CFDF11TPSB2KLKB1PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021072198-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2021-04-15 | — | — | WO | disclosed |