Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD5 | P21918 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | OXTR | P30559 | 1/20 | 0.37 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23229137 | 0.92 | KDM4E (0.44) | L3MBTL1KDM4EDRD1DRD4DRD5 | |
| SCHEMBL29852605 | 0.92 | CFD (0.46) | L3MBTL1KDM4ETBXAS1DRD1DRD4 | |
| SCHEMBL23218955 | 0.92 | CFD (0.46) | L3MBTL1KDM4ETBXAS1DRD1DRD4 | |
| SCHEMBL23218348 | 0.87 | POLB (0.44) | KDM4ETBXAS1DRD1DRD4DRD5 | |
| SCHEMBL29852804 | 0.87 | POLB (0.44) | KDM4ETBXAS1DRD1DRD4DRD5 | |
| SCHEMBL29853035 | 0.81 | CFD (0.54) | L3MBTL1KDM4EDRD1DRD4DRD5 | |
| SCHEMBL23218694 | 0.81 | CFD (0.54) | L3MBTL1KDM4EDRD1DRD4DRD5 | |
| SCHEMBL29852375 | 0.81 | CFD (0.48) | KDM4EALDH1A1CYP2D6 | |
| SCHEMBL23218164 | 0.81 | CFD (0.48) | KDM4EALDH1A1CYP2D6 | |
| SCHEMBL23218611 | 0.79 | CFD (0.45) | TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021072198-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2021-04-15 | — | — | WO | disclosed |