Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1792326 | 0.85 | TSHR (0.55) | TBXAS1PKML3MBTL1SMN1; SMN2KDM4E | |
| SCHEMBL7890168 | 0.85 | TBXAS1 (0.59) | TBXAS1PKMCYP4F2CYP4A11L3MBTL1 | |
| SCHEMBL24200238 | 0.84 | TBXAS1 (0.49) | TBXAS1PKMCYP4F2CYP4A11HSD17B10 | |
| SCHEMBL68340 | 0.84 | PKM (0.60) | TBXAS1PKMCYP4F2CYP4A11HSD17B10 | |
| SCHEMBL28448312 | 0.83 | KDM4E (0.44) | L3MBTL1KDM4ETSHRALDH1A1 | |
| SCHEMBL18050464 | 0.82 | CYP4F2 (0.50) | TBXAS1PKMCYP4F2CYP4A11HSD17B10 | |
| SCHEMBL28392981 | 0.82 | TBXAS1 (0.50) | TBXAS1PKMCYP4F2CYP4A11HSD17B10 | |
| SCHEMBL6367595 | 0.81 | TBXAS1 (0.59) | TBXAS1PKMCYP4F2CYP4A11L3MBTL1 | |
| SCHEMBL16502248 | 0.81 | TBXAS1 (0.52) | TBXAS1PKMCYP4F2CYP4A11HSD17B10 | |
| SCHEMBL21455699 | 0.81 | TBXAS1 (0.49) | TBXAS1PKMCYP4F2CYP4A11L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021072198-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2021-04-15 | — | — | WO | disclosed |