Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.47 |
| ▸ | PPARD | Q03181 | 5/20 | 0.47 |
| ▸ | PPARA | Q07869 | 5/20 | 0.47 |
| ▸ | TERT | O14746 | 3/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | BLM | P54132 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | FABP4 | P15090 | 3/20 | 0.47 |
| ▸ | F7 | P08709 | 3/20 | 0.47 |
| ▸ | F3 | P13726 | 3/20 | 0.47 |
| ▸ | TOP1 | P11387 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2322942 | 1.00 | PPARG (0.47) | PPARGPPARDPPARATERTPTPN1 | |
| SCHEMBL11148247 | 0.86 | TOP1 (0.61) | PPARGPPARDPPARATERTPTPN1 | |
| SCHEMBL12197494 | 0.85 | ALDH1A1 (0.41) | PPARGPPARDPPARATERTPTPN1 | |
| SCHEMBL27458768 | 0.82 | AKR1B1 (0.48) | PPARGPPARDPPARATERTPTPN1 | |
| SCHEMBL12197479 | 0.80 | TOP1 (0.41) | PPARGPPARDPPARATERTPTPN1 | |
| SCHEMBL19602146 | 0.80 | PPARG (0.59) | PPARGPPARDPPARATERTPTPN1 | |
| SCHEMBL16863887 | 0.78 | LPAR3 (0.38) | F7F3FAAHALDH1A1 | |
| SCHEMBL27677868 | 0.78 | LPAR3 (0.38) | F7F3FAAHALDH1A1 | |
| SCHEMBL28146382 | 0.78 | ADRB2 (0.36) | ATMALDH1A1CYP3A4HPGD | |
| SCHEMBL9199082 | 0.77 | F7 (0.50) | PPARGPPARDPPARATERTPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2534140-B1 | EFFICIENT METHODS FOR Z- OR CIS-SELECTIVE CROSS-METATHESIS | TRUSTEES BOSTON COLLEGE (US) | 2018-04-11 | — | — | EP | disclosed |
| US-8598400-B2 | Efficient methods for Z- or cis-selective cross-metathesis | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2013-12-03 | — | — | US | disclosed |
| US-8552242-B2 | — | — | 2013-10-08 | — | — | US | disclosed |
| EP-2534140-A1 | EFFICIENT METHODS FOR Z- OR CIS-SELECTIVE CROSS-METATHESIS | Trustees of Boston College (US) | 2012-12-19 | — | — | EP | disclosed |
| US-20110245477-A1 | EFFICIENT METHODS FOR Z- OR CIS-SELECTIVE CROSS-METATHESIS | TRUSTEES OF BOSTON COLLEGE (US) | 2011-10-06 | — | — | US | disclosed |
| WO-2011097642-A1 | EFFICIENT METHODS FOR Z- OR CIS-SELECTIVE CROSS-METATHESIS | TRUSTEES OF BOSTON COLLEGE (US) | 2011-08-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110245477-A1 | EFFICIENT METHODS FOR Z- OR CIS-SELECTIVE CROSS-METATHESIS | PAICS, COASY, CYP51A1 | PPARG 3643/4885PPARD 4019/4885PPARA 3232/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.