⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13928103 | 0.66 | — | — | |
| SCHEMBL23892439 | 0.64 | — | — | |
| SCHEMBL3509447 | 0.64 | — | — | |
| SCHEMBL19017625 | 0.62 | CYP11B2 (0.33) | — | |
| SCHEMBL11381367 | 0.61 | — | — | |
| SCHEMBL23588573 | 0.60 | TRPA1 (0.31) | — | |
| SCHEMBL27893855 | 0.60 | — | — | |
| SCHEMBL24224644 | 0.60 | — | — | |
| SCHEMBL15164784 | 0.59 | — | — | |
| SCHEMBL5067973 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021072203-A1 | TGFBETAR1 INHIBITOR-ASGR ANTIBODY CONJUGATES AND USES THEREOF | SILVERBACK THERAPEUTICS, INC. (US) | 2021-04-15 | — | — | WO | disclosed |