Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.31 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1382794 | 0.84 | ALOX15 (0.38) | — | |
| SCHEMBL1383312 | 0.84 | ALOX15 (0.38) | — | |
| SCHEMBL2328968 | 0.71 | ALDH1A1 (0.45) | CDK5CDK5R1 | |
| SCHEMBL12826129 | 0.65 | HTR2C (0.40) | CDK5CDK5R1NPSR1RXFP1 | |
| SCHEMBL1385607 | 0.65 | NPC1 (0.38) | — | |
| SCHEMBL1383964 | 0.65 | NPC1 (0.38) | — | |
| SCHEMBL1383142 | 0.65 | NOTUM (0.39) | NPSR1 | |
| SCHEMBL1383436 | 0.65 | HPGD (0.46) | — | |
| SCHEMBL1386553 | 0.65 | NOTUM (0.39) | NPSR1 | |
| SCHEMBL1382864 | 0.65 | CNR2 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904455-B1 | PYRIDAZINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2011-08-17 | — | — | EP | claimed |