SCHEMBL23229948

SCHEMBL23229948

N=C(N)NCCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1ccccc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ NPY4R P50391 12/20 0.60
▸ NPY1R P25929 7/20 0.60
▸ NPY2R P49146 5/20 0.60
▸ NPY5R Q15761 5/20 0.60
▸ KISS1R Q969F8 8/20 0.55
▸ OPRD1 P41143 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29988484 0.96 NPY4R (0.64) NPY4RNPY1RNPY2RNPY5RKISS1R
SCHEMBL30450301 0.96 NPY4R (0.64) NPY4RNPY1RNPY2RNPY5RKISS1R
SCHEMBL29531433 0.96 NPY4R (0.64) NPY4RNPY1RNPY2RNPY5RKISS1R
SCHEMBL29531172 0.96 NPY4R (0.64) NPY4RNPY1RNPY2RNPY5RKISS1R
SCHEMBL29780055 0.94 NPY4R (0.64) NPY4RNPY1RNPY2RNPY5RKISS1R
SCHEMBL31256959 0.94 NPY4R (0.64) NPY4RNPY1RNPY2RNPY5RKISS1R
SCHEMBL31512205 0.94 NPY4R (0.64) NPY4RNPY1RNPY2RNPY5RKISS1R
SCHEMBL29637467 0.93 NPY4R (0.66) NPY4RNPY1RNPY2RNPY5RKISS1R
SCHEMBL31575310 0.93 NPY4R (0.60) NPY4RNPY1RNPY2RNPY5RKISS1R
SCHEMBL13563452 0.93 NPY4R (0.67) NPY4RNPY1RNPY2RNPY5R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210106506-A1 METHODS FOR COSMETIC SKIN REMODELING ELC MANAGEMENT LLC 2021-04-15 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210106506-A1 METHODS FOR COSMETIC SKIN REMODELING CUTA, PLOD3, KRT18 NPY4R 4427/4885NPY1R 4256/4885NPY2R 4705/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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