Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.53 |
| ▸ | NQO2 | P16083 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.46 |
| ▸ | MEN1 | O00255 | 9/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | BRAF | P15056 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | TNKS | O95271 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.43 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11486200 | 0.85 | MAPT (0.51) | MAPTNQO2KMT2AMEN1ALDH1A1 | |
| SCHEMBL3361349 | 0.83 | MAPT (0.64) | MAPTNQO2KMT2AMEN1ALDH1A1 | |
| SCHEMBL2323398 | 0.81 | MAPT (0.61) | MAPTNQO2KMT2AMEN1ALDH1A1 | |
| SCHEMBL27632460 | 0.77 | MAPT (0.57) | MAPTNQO2KMT2AMEN1ALDH1A1 | |
| SCHEMBL29273189 | 0.77 | KMT2A (0.60) | MAPTNQO2KMT2AMEN1ALDH1A1 | |
| SCHEMBL6734270 | 0.75 | MAPT (0.55) | MAPTNQO2KMT2AMEN1ALDH1A1 | |
| SCHEMBL2615714 | 0.75 | MAPT (0.55) | MAPTNQO2KMT2AMEN1ALDH1A1 | |
| SCHEMBL19926009 | 0.75 | MAPT (0.55) | MAPTNQO2KMT2AMEN1ALDH1A1 | |
| SCHEMBL2322085 | 0.74 | ALDH1A1 (0.44) | MAPTKMT2AMEN1ALDH1A1NPC1 | |
| SCHEMBL2318469 | 0.74 | ALDH1A1 (0.44) | MAPTNQO2KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011094890-A1 | PHENYLALANINE DERIVATIVES AND THEIR USE AS NON-PEPTIDE GLP-1 RECEPTOR MODULATORS | ARGUSINA INC. (US) | 2011-08-11 | — | — | WO | disclosed |