Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NQO2 | P16083 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | BRAF | P15056 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | TNKS | O95271 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.42 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2323095 | 0.85 | MAPT (0.53) | MAPTNPC1RAB9AALDH1A1LMNA | |
| SCHEMBL3361349 | 0.82 | MAPT (0.64) | MAPTNPC1RAB9AALDH1A1LMNA | |
| SCHEMBL395933 | 0.82 | PGR (0.46) | MAPTALDH1A1LMNAHPGDNQO2 | |
| SCHEMBL27632460 | 0.75 | MAPT (0.57) | MAPTNPC1RAB9AALDH1A1LMNA | |
| SCHEMBL29273189 | 0.75 | KMT2A (0.60) | MAPTNPC1RAB9AALDH1A1LMNA | |
| SCHEMBL11606898 | 0.74 | MMP3 (0.43) | ALDH1A1PGRTNKS | |
| SCHEMBL19926009 | 0.74 | MAPT (0.55) | MAPTNPC1RAB9AALDH1A1LMNA | |
| SCHEMBL2615714 | 0.74 | MAPT (0.55) | MAPTNPC1RAB9AALDH1A1LMNA | |
| SCHEMBL6734270 | 0.74 | MAPT (0.55) | MAPTNPC1RAB9AALDH1A1LMNA | |
| SCHEMBL4072821 | 0.73 | MAPT (0.68) | MAPTALDH1A1LMNAPKMHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4217286-A | 5-Phenyl-2-furancarboximidamides | MORTON-NORWICH PRODUCTS, INC. (US) | 1980-08-12 | — | — | US | disclosed |
| US-3946049-A | 5-PHENYL-2-FURAMIDOXIMES | MORTON-NORWICH PRODUCTS, INC. (US) | 1976-03-23 | — | — | US | disclosed |