SCHEMBL2323319

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12440269	0.95	MAP4K1 (0.40)	METMAP4K1NTRK1DYRK1AWNT1
	SCHEMBL2365416	0.95	MAP4K1 (0.40)	METMAP4K1NTRK1DYRK1AWNT1
	SCHEMBL2323396	0.95	MAP4K1 (0.40)	METMAP4K1NTRK1DYRK1AWNT1
	SCHEMBL12439733	0.92	MET (0.46)	METNTRK1DYRK1AWNT1JAK2
	SCHEMBL12441209	0.92	MET (0.47)	METNTRK1DYRK1AWNT1JAK2
	SCHEMBL12440209	0.91	MET (0.43)	METNTRK1DYRK1AWNT1JAK2
	SCHEMBL2325237	0.90	EGFR (0.43)	METMAP4K1NTRK1DYRK1AWNT1
	SCHEMBL2364303	0.90	MET (0.41)	METNTRK1DYRK1AWNT1JAK2
	SCHEMBL2329547	0.90	MET (0.41)	METMAP4K1JAK2JAK1TYK2
	SCHEMBL2327026	0.89	FGFR1 (0.44)	METMAP4K1FGFR1FGFR2FGFR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.