SCHEMBL2329547

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12440059	0.92	MET (0.45)	METFEN1BTKKHKRAF1
	SCHEMBL2327444	0.92	MET (0.41)	METFEN1BTKKHKRAF1
	SCHEMBL2327026	0.90	FGFR1 (0.44)	METMAP4K1RAF1MAP2K1
	SCHEMBL2323319	0.90	MET (0.43)	METMAP4K1JAK2JAK1TYK2
	SCHEMBL2323396	0.86	MAP4K1 (0.40)	METMAP4K1FEN1JAK2JAK1
	SCHEMBL2365416	0.86	MAP4K1 (0.40)	METMAP4K1FEN1JAK2JAK1
	SCHEMBL12440269	0.86	MAP4K1 (0.40)	METMAP4K1FEN1JAK2JAK1
	SCHEMBL2320474	0.85	MAP4K1 (0.53)	METMAP4K1JAK2JAK1TYK2
	Hydrochloric Acid SCHEMBL13834975	0.85	MAP4K1 (0.52)	METMAP4K1
	SCHEMBL2323346	0.84	FEN1 (0.47)	METFEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.