Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD5 | P21918 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.40 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12367112 | 0.84 | TDP1 (0.42) | ALDH1A1POLBUSP2BRCA1TSHR | |
| SCHEMBL1443579 | 0.81 | TRIM24 (0.60) | ALDH1A1HTR7MEN1KMT2ATRIM24 | |
| SCHEMBL29377692 | 0.81 | TRIM24 (0.60) | ALDH1A1HTR7MEN1KMT2ATRIM24 | |
| SCHEMBL6313563 | 0.80 | NOTUM (0.56) | KDM4ENOTUM | |
| SCHEMBL18003663 | 0.80 | HTR7 (0.41) | ALDH1A1POLBHTR7DRD2DRD4 | |
| SCHEMBL29442412 | 0.80 | ALDH1A1 (0.64) | ALDH1A1HTR7DRD3GAAKDM4E | |
| SCHEMBL1444185 | 0.80 | ALDH1A1 (0.64) | ALDH1A1HTR7DRD3GAAKDM4E | |
| SCHEMBL1418736 | 0.80 | ALDH1A1 (0.61) | ALDH1A1HTR7MEN1KMT2APKM | |
| SCHEMBL7977661 | 0.80 | TRIM24 (0.63) | ALDH1A1POLBUSP2TRIM24TRIM33 | |
| SCHEMBL30770827 | 0.80 | ALDH1A1 (0.61) | ALDH1A1HTR7MEN1KMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011094890-A1 | PHENYLALANINE DERIVATIVES AND THEIR USE AS NON-PEPTIDE GLP-1 RECEPTOR MODULATORS | ARGUSINA INC. (US) | 2011-08-11 | — | — | WO | disclosed |