Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.41 |
| ▸ | CNR2 | P34972 | 9/20 | 0.41 |
| ▸ | BCHE | P06276 | 4/20 | 0.40 |
| ▸ | ACHE | P22303 | 4/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1259555 | 0.83 | MAPT (0.51) | ABCB1MAPTKDM4EMEN1CYP3A4 | |
| SCHEMBL12893120 | 0.81 | ABCB1 (0.43) | ABCB1MAPTKDM4EMEN1CYP3A4 | |
| SCHEMBL2329785 | 0.79 | MAPT (0.42) | ABCB1MAPTKDM4EMEN1CYP3A4 | |
| SCHEMBL12918131 | 0.77 | ABCB1 (0.40) | ABCB1MAPTKDM4EMEN1CYP3A4 | |
| SCHEMBL2323455 | 0.76 | CSNK2A2 (0.45) | ABCB1MAPTKDM4EMEN1CYP3A4 | |
| SCHEMBL12893115 | 0.75 | ABCB1 (0.38) | ABCB1MAPTKDM4EMEN1CYP3A4 | |
| SCHEMBL19833677 | 0.73 | TP53 (0.67) | ABCB1MAPTKDM4EMEN1CYP3A4 | |
| SCHEMBL30888820 | 0.73 | TP53 (0.67) | ABCB1MAPTKDM4EMEN1CYP3A4 | |
| SCHEMBL15087677 | 0.73 | CNR2 (0.59) | KDM4EMEN1KMT2ACNR2 | |
| SCHEMBL17940134 | 0.72 | MAPT (0.49) | ABCB1MAPTKDM4EMEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1948633-B1 | 3 -HYDROXYFLAVONE DERIVATIVES FOR THE DETECTION AND THE QUANTIFICATION OF CELL APOPTOSIS | CENTRE NAT RECH SCIENT (FR) | 2011-08-10 | — | — | EP | claimed |
| JP-2009511566-A | — | — | 2009-03-19 | — | — | JP | claimed |
| EP-1948633-A2 | 3 -HYDROXYFLAVONE DERIVATIVES FOR THE DETECTION AND THE QUANTIFICATION OF CELL APOPTOSIS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2008-07-30 | — | — | EP | claimed |
| WO-2007057782-A2 | 3 -HYDROXYFLAVONE DERIVATIVES FOR THE DETECTION AND THE QUANTIFICATION OF CELL APOPTOSIS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2007-05-24 | — | — | WO | claimed |
| EP-1948633-A2 | 3 -HYDROXYFLAVONE DERIVATIVES FOR THE DETECTION AND THE QUANTIFICATION OF CELL APOPTOSIS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2008-07-30 | — | — | EP | disclosed |
| WO-2007057782-A2 | 3 -HYDROXYFLAVONE DERIVATIVES FOR THE DETECTION AND THE QUANTIFICATION OF CELL APOPTOSIS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2007-05-24 | — | — | WO | disclosed |