Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.49 |
| ▸ | TP53 | P04637 | 7/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.48 |
| ▸ | MEN1 | O00255 | 7/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | CASP1 | P29466 | 3/20 | 0.48 |
| ▸ | CASP7 | P55210 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | RET | P07949 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17940149 | 0.86 | ALDH1A1 (0.39) | MAPTKDM4ETP53CYP3A4MEN1 | |
| SCHEMBL19833677 | 0.85 | TP53 (0.67) | MAPTKDM4ETP53RXFP1CYP3A4 | |
| SCHEMBL30888820 | 0.85 | TP53 (0.67) | MAPTKDM4ETP53RXFP1CYP3A4 | |
| SCHEMBL17944028 | 0.82 | TP53 (0.70) | MAPTKDM4ETP53RXFP1CYP3A4 | |
| SCHEMBL17940142 | 0.82 | CYP3A4 (0.68) | MAPTKDM4ETP53CYP3A4MEN1 | |
| SCHEMBL1259555 | 0.79 | MAPT (0.51) | MAPTKDM4ETP53RXFP1CYP3A4 | |
| SCHEMBL17943841 | 0.79 | KDM4E (0.52) | MAPTKDM4ETP53CYP3A4MEN1 | |
| SCHEMBL17940164 | 0.78 | KDM4E (0.56) | MAPTKDM4ETP53CYP3A4MEN1 | |
| SCHEMBL17944301 | 0.77 | KDM4E (0.46) | MAPTKDM4ETP53RXFP1CYP3A4 | |
| SCHEMBL17944015 | 0.75 | KDM4E (0.57) | MAPTKDM4ETP53CYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9840488-B2 | Carbon monoxide releasing molecules and associated methods | UTAH STATE UNIVERSITY (US) | 2017-12-12 | — | — | US | disclosed |
| US-9840488-B2 | Carbon monoxide releasing molecules and associated methods | UTAH STATE UNIVERSITY (US) | 2017-12-12 | — | — | US | disclosed |
| US-9840488-B2 | Carbon monoxide releasing molecules and associated methods | UTAH STATE UNIVERSITY (US) | 2017-12-12 | — | — | US | disclosed |
| WO-2016123141-A1 | CARBON MONOXIDE RELEASING MOLECULES AND ASSOCIATED METHODS | BERREAU LISA M (US) | 2016-08-04 | — | — | WO | disclosed |
| US-20160214955-A1 | Carbon Monoxide Releasing Molecules and Associated Methods | UTAH STATE UNIVERSITY (US) | 2016-07-28 | — | — | US | disclosed |
| US-20160214955-A1 | Carbon Monoxide Releasing Molecules and Associated Methods | UTAH STATE UNIVERSITY (US) | 2016-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160214955-A1 | Carbon Monoxide Releasing Molecules and Associated Methods | MB, CORO1C, CYCS | MAPT 2371/4885KDM4E 1691/4885TP53 1292/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.