Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 9/20 | 0.38 |
| ▸ | TP53 | P04637 | 7/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 4/20 | 0.35 |
| ▸ | CSNK2B | P67870 | 4/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CASP1 | P29466 | 2/20 | 0.33 |
| ▸ | CASP7 | P55210 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12893120 | 0.90 | ABCB1 (0.43) | ABCB1MAPTTP53RXFP1KDM4E | |
| SCHEMBL12918131 | 0.85 | ABCB1 (0.40) | ABCB1MAPTTP53RXFP1KDM4E | |
| SCHEMBL2323461 | 0.75 | ABCB1 (0.45) | ABCB1MAPTTP53RXFP1KDM4E | |
| SCHEMBL1259555 | 0.73 | MAPT (0.51) | ABCB1MAPTTP53RXFP1KDM4E | |
| SCHEMBL2323455 | 0.70 | CSNK2A2 (0.45) | ABCB1MAPTTP53RXFP1KDM4E | |
| SCHEMBL2329785 | 0.69 | MAPT (0.42) | ABCB1MAPTTP53RXFP1KDM4E | |
| SCHEMBL30888820 | 0.66 | TP53 (0.67) | ABCB1MAPTTP53RXFP1KDM4E | |
| SCHEMBL19833677 | 0.66 | TP53 (0.67) | ABCB1MAPTTP53RXFP1KDM4E | |
| SCHEMBL17940134 | 0.65 | MAPT (0.49) | ABCB1MAPTTP53RXFP1KDM4E | |
| SCHEMBL4035228 | 0.64 | ABCB1 (0.58) | ABCB1MAPTTP53RXFP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7880021-B2 | reacting 6-bromomethyl-4'-(diethylamino)-3-hydroxyflavone with dodecylmethylamine to form the corresponding tertiary amine (4'-(diethylamino)-6-(dodecyl(methyl)aminomethyl)-3-hydroxyflavone); and reacting the product of step a. with propansultone; use in biomembrane studies; Alzheimer's disease, cancer | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2011-02-01 | — | — | US | disclosed |
| US-20090269793-A1 | Compounds and Kits for the Detection and the Quantification of Cell Apoptosis | Centre National De La Recherche Scientifiique (CNRS) | 2009-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090269793-A1 | Compounds and Kits for the Detection and the Quantification of Cell Apoptosis | BAX, CASP3, BCL2 | ABCB1 1401/4885MAPT 4847/4885TP53 160/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.