Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 4/20 | 0.56 |
| ▸ | PRKCA | P17252 | 3/20 | 0.52 |
| ▸ | ABL1 | P00519 | 3/20 | 0.51 |
| ▸ | BCR | P11274 | 3/20 | 0.51 |
| ▸ | TEK | Q02763 | 2/20 | 0.46 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.46 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.44 |
| ▸ | KDR | P35968 | 2/20 | 0.44 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.44 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | PRKACA | P17612 | 1/20 | 0.42 |
| ▸ | PRKACG | P22612 | 1/20 | 0.42 |
| ▸ | PRKACB | P22694 | 1/20 | 0.42 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 2/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2330503 | 0.97 | IGF1R (0.53) | IGF1RPRKCAABL1BCRTEK | |
| SCHEMBL2329464 | 0.91 | PRKCA (0.62) | IGF1RPRKCAABL1BCRTEK | |
| SCHEMBL2322576 | 0.84 | EPHB4 (0.59) | IGF1RPRKCATEKEPHB4PTK2 | |
| SCHEMBL2323589 | 0.82 | CTSC (0.53) | IGF1RPRKCAABL1BCRKDR | |
| SCHEMBL2327107 | 0.81 | FGFR2 (0.56) | IGF1RKDRFGFR2FGFR3EGFR | |
| SCHEMBL2330310 | 0.80 | CDK1 (0.47) | PRKCAABL1BCRKDRFGFR2 | |
| SCHEMBL8837813 | 0.79 | ABL1 (0.72) | IGF1RPRKCAABL1BCRFGFR2 | |
| SCHEMBL8837807 | 0.78 | PRKCA (0.79) | PRKCAABL1BCRFGFR2FGFR3 | |
| SCHEMBL2325853 | 0.76 | CDK1 (0.50) | KDRFGFR2FGFR3EGFRCDK2 | |
| SCHEMBL2323714 | 0.73 | CDK1 (0.49) | PRKCAABL1BCRKDRFGFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2356107-A1 | SUBSTITUTED (PYRIDYL)-AZINYLAMINE DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2011-08-17 | — | — | EP | disclosed |
| WO-2010055077-A1 | SUBSTITUTED (PYRIDYL)-AZINYLAMINE DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE SA (FR) | 2010-05-20 | — | — | WO | disclosed |