Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 4/20 | 0.53 |
| ▸ | PRKCA | P17252 | 3/20 | 0.51 |
| ▸ | ABL1 | P00519 | 3/20 | 0.49 |
| ▸ | BCR | P11274 | 3/20 | 0.49 |
| ▸ | KDR | P35968 | 3/20 | 0.44 |
| ▸ | CDK2 | P24941 | 2/20 | 0.44 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | CDK4 | P11802 | 1/20 | 0.44 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.44 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.44 |
| ▸ | CCND1 | P24385 | 1/20 | 0.44 |
| ▸ | CCND3 | P30281 | 1/20 | 0.44 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.44 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.44 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.44 |
| ▸ | CDK7 | P50613 | 1/20 | 0.44 |
| ▸ | CCNH | P51946 | 1/20 | 0.44 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.44 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2323561 | 0.97 | IGF1R (0.56) | IGF1RPRKCAABL1BCRKDR | |
| SCHEMBL2329464 | 0.88 | PRKCA (0.62) | IGF1RPRKCAABL1BCRKDR | |
| SCHEMBL2322576 | 0.81 | EPHB4 (0.59) | IGF1RPRKCAKDRCDK2CDK1 | |
| SCHEMBL2323589 | 0.80 | CTSC (0.53) | IGF1RPRKCAABL1BCRKDR | |
| SCHEMBL2327107 | 0.79 | FGFR2 (0.56) | IGF1RKDRCDK2CCNB2CDK1 | |
| SCHEMBL2330310 | 0.78 | CDK1 (0.47) | PRKCAABL1BCRKDRCDK2 | |
| SCHEMBL2321693 | 0.78 | CDK1 (0.65) | IGF1RPRKCAABL1BCRKDR | |
| SCHEMBL8837813 | 0.76 | ABL1 (0.72) | IGF1RPRKCAABL1BCRCDK2 | |
| SCHEMBL8837807 | 0.75 | PRKCA (0.79) | PRKCAABL1BCRCDK2CCNB2 | |
| SCHEMBL2325853 | 0.73 | CDK1 (0.50) | KDRCDK2CCNB2CDK1CDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2356107-A1 | SUBSTITUTED (PYRIDYL)-AZINYLAMINE DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2011-08-17 | — | — | EP | claimed |
| WO-2010055077-A1 | SUBSTITUTED (PYRIDYL)-AZINYLAMINE DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE SA (FR) | 2010-05-20 | — | — | WO | claimed |