SCHEMBL2323686

SCHEMBL2323686

COC(=O)[C@H](CCSC)NC(=O)c1ccccc1

nearest known ligand 0.74

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.74
TAS1R3 Q7RTX0 1/20 0.64
TAS1R1 Q7RTX1 1/20 0.64
KMT2A Q03164 2/20 0.62
MEN1 O00255 1/20 0.62
ALDH1A1 P00352 1/20 0.62
CRHBP P24387 1/20 0.62
CRHR2 Q13324 1/20 0.62
FNTA P49354 3/20 0.57
FNTB P49356 3/20 0.57
GAA P10253 2/20 0.56
CYP3A4 P08684 1/20 0.56
CYP2C19 P33261 1/20 0.56
NPC1 O15118 1/20 0.55
CA2 P00918 2/20 0.54
CA1 P00915 1/20 0.54
CCR1 P32246 1/20 0.54
APOBEC3G Q9HC16 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18095164 1.00 L3MBTL1 (0.74) L3MBTL1TAS1R3TAS1R1KMT2AMEN1
SCHEMBL27974663 0.89 L3MBTL1 (0.63) L3MBTL1TAS1R3TAS1R1KMT2AMEN1
SCHEMBL2330865 0.89 L3MBTL1 (0.63) L3MBTL1TAS1R3TAS1R1KMT2AMEN1
SCHEMBL9461939 0.87 CA2 (0.69) KMT2AMEN1ALDH1A1CRHBPCRHR2
SCHEMBL1158031 0.87 CA2 (0.69) KMT2AMEN1ALDH1A1CRHBPCRHR2
SCHEMBL1158033 0.87 CA2 (0.69) KMT2AMEN1ALDH1A1CRHBPCRHR2
SCHEMBL13525007 0.87 L3MBTL1 (0.71) L3MBTL1TAS1R3TAS1R1KMT2AALDH1A1
SCHEMBL2327433 0.87 L3MBTL1 (0.60) L3MBTL1TAS1R3TAS1R1KMT2AMEN1
SCHEMBL27974764 0.87 L3MBTL1 (0.60) L3MBTL1TAS1R3TAS1R1KMT2AMEN1
SCHEMBL8106910 0.86 L3MBTL1 (0.74) L3MBTL1TAS1R3TAS1R1KMT2AFNTA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180070612-A1 RUMEN BY-PASS ANIMAL FEED COMPOSITION AND METHOD OF MAKING SAME WAN FENG (US) 2018-03-15 US claimed
EP-3273795-A1 RUMEN BY-PASS ANIMAL FEED COMPOSITION AND METHOD OF MAKING SAME Benemilk Oy (FI) 2018-01-31 EP claimed
WO-2016154574-A1 RUMEN BY-PASS ANIMAL FEED COMPOSITION AND METHOD OF MAKING SAME BENEMILK OY (FI) 2016-09-29 WO claimed
US-20180070612-A1 RUMEN BY-PASS ANIMAL FEED COMPOSITION AND METHOD OF MAKING SAME WAN FENG (US) 2018-03-15 US disclosed
EP-3273795-A1 RUMEN BY-PASS ANIMAL FEED COMPOSITION AND METHOD OF MAKING SAME Benemilk Oy (FI) 2018-01-31 EP disclosed
EP-2356979-B1 ANTI-WRINKLE AGENTS POLA CHEM IND INC (JP) 2017-10-25 EP disclosed
EP-3173063-A1 ANTI-WRINKLE AGENTS Pola Chemical Industries Inc. (JP) 2017-05-31 EP disclosed
WO-2016154574-A1 RUMEN BY-PASS ANIMAL FEED COMPOSITION AND METHOD OF MAKING SAME BENEMILK OY (FI) 2016-09-29 WO disclosed
US-8835498-B2 Anti-wrinkle agents POLA CHEMICAL INDUSTRIES INC. (JP) 2014-09-16 US disclosed
US-20110245343-A1 ANTI-WRINKLE AGENTS POLA CHEMICAL INDUSTRIES INC. (JP) 2011-10-06 US disclosed
EP-2356979-A1 ANTI-WRINKLE AGENTS Pola Chemical Industries Inc. (JP) 2011-08-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110245343-A1 ANTI-WRINKLE AGENTS GLA, H1-4, H1-3 L3MBTL1 1901/4885TAS1R3 746/4885TAS1R1 809/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.