Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 4/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.42 |
| ▸ | CNR1 | P21554 | 4/20 | 0.39 |
| ▸ | CNR2 | P34972 | 4/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.37 |
| ▸ | UQCRB | P14927 | 1/20 | 0.37 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL11421230 | 0.90 | ALDH1A1 (0.60) | ALDH1A1TSHRTDP1ESR1ESR2 | |
| SCHEMBL51085 | 0.90 | ALDH1A1 (0.60) | ALDH1A1TSHRTDP1ESR1ESR2 | |
| SCHEMBL11645702 | 0.90 | ALDH1A1 (0.60) | ALDH1A1TSHRTDP1ESR1ESR2 | |
| Bicarbonate SCHEMBL5604857 | 0.89 | ALDH1A1 (0.54) | ALDH1A1TSHRTDP1ESR1ESR2 | |
| Formaldehyde SCHEMBL674141 | 0.89 | ALDH1A1 (0.54) | ALDH1A1TSHRTDP1ESR1ESR2 | |
| Water SCHEMBL27929084 | 0.88 | ALDH1A1 (0.58) | ALDH1A1TSHRTDP1ESR1ESR2 | |
| SCHEMBL29110944 | 0.88 | ALDH1A1 (0.58) | ALDH1A1TSHRTDP1ESR1ESR2 | |
| Barium SCHEMBL30124829 | 0.88 | ALDH1A1 (0.58) | ALDH1A1TSHRTDP1ESR1ESR2 | |
| Benzene SCHEMBL27946537 | 0.88 | ALDH1A1 (0.58) | ALDH1A1TSHRTDP1ESR1ESR2 | |
| Ethylene SCHEMBL28540957 | 0.86 | ALDH1A1 (0.56) | ALDH1A1TSHRTDP1ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2357269-A1 | ACIDIC ZINC PLATING BATH | Yuken Industry Co., Ltd. (JP) | 2011-08-17 | — | — | EP | disclosed |