SCHEMBL2323726

SCHEMBL2323726

O=C(Cl)c1ccc(C(F)(F)F)cc1[N+](=O)[O-]

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPD P32754 3/20 0.59
FLT1 P17948 1/20 0.57
FLT4 P35916 1/20 0.57
KDR P35968 1/20 0.57
ALDH1A1 P00352 4/20 0.53
TDP1 Q9NUW8 2/20 0.53
CYP3A4 P08684 2/20 0.53
HPGD P15428 1/20 0.53
ALOX15 P16050 1/20 0.53
TSHR P16473 1/20 0.53
HIF1A Q16665 1/20 0.53
TXNRD1 Q16881 1/20 0.53
TXNRD3 Q86VQ6 1/20 0.53
TXNRD2 Q9NNW7 1/20 0.53
KCNMA1 Q12791 1/20 0.50
MAPT P10636 4/20 0.48
AKR1B1 P15121 2/20 0.48
AKR1C4 P17516 2/20 0.48
AKR1C3 P42330 2/20 0.48
AKR1C2 P52895 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29079008 0.98 HPD (0.58) HPDFLT1FLT4KDRALDH1A1
SCHEMBL8491405 0.88 HPD (0.47) HPDFLT1FLT4KDRALDH1A1
SCHEMBL442397 0.85 HPD (0.60) HPDFLT1FLT4KDRALDH1A1
SCHEMBL5452045 0.85 HPD (0.60) HPDFLT1FLT4KDRALDH1A1
SCHEMBL8492671 0.84 NPC1 (0.51) HPDFLT1FLT4KDRALDH1A1
Ammonia Solution, Strong SCHEMBL28953061 0.84 HPD (0.59) HPDFLT1FLT4KDRALDH1A1
SCHEMBL165527 0.84 HPD (0.59) HPDFLT1FLT4KDRALDH1A1
Hydrochloric Acid SCHEMBL11776053 0.84 HPD (0.59) HPDFLT1FLT4KDRALDH1A1
SCHEMBL4658862 0.84 HPD (0.62) HPDFLT1FLT4KDRALDH1A1
SCHEMBL4167623 0.83 FLT1 (0.60) HPDFLT1FLT4KDRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250282960-A1 PAINT THINNER FORMULATION HINDUSTAN PETROLEUM CORPORATION LIMITED (IN) 2025-09-11 US claimed
CN-116640063-B Preparation method of nitenpyram 安徽贝克制药股份有限公司 2025-03-14 CN claimed
CN-116640063-A Preparation method of nitenpyram 安徽贝克制药股份有限公司 2023-08-25 CN claimed
US-9783485-B1 Crystalline inhibitor of 4-hydroxyphenylpyruvate dioxygenase, and a process of synthesis and crystallization thereof DIPHARMA S.A. (CH) 2017-10-10 US claimed
EP-3089740-A1 PHARMACEUTICAL COMPOSITION Cycle Pharmaceuticals Ltd. (GB) 2016-11-09 EP claimed
WO-2015101794-A1 PHARMACEUTICAL COMPOSITION CYCLE PHARMACEUTICALS LTD (GB) 2015-07-09 WO claimed
CN-102976948-B Method for preparing nitisinone ZHENGZHOU DAMING MEDICINE SCIENCE & TECHNOLOGY CO LTD 2014-07-09 CN claimed
CN-103304480-A Benzoyl parazole compound as well as synthesis method thereof and application of same as herbicide HEILONGJIANG SHENGNONG SCIENCE AND TECHNOLOGY DEV CO LTD 2013-09-18 CN claimed
CN-102976948-A Method for preparing nitisinone ZHENGZHOU DAMING MEDICINE SCIENCE & TECHNOLOGY CO LTD 2013-03-20 CN claimed
US-20250282960-A1 PAINT THINNER FORMULATION HINDUSTAN PETROLEUM CORPORATION LIMITED (IN) 2025-09-11 US disclosed
CN-116640063-B Preparation method of nitenpyram 安徽贝克制药股份有限公司 2025-03-14 CN disclosed
CN-116640063-B Preparation method of nitenpyram 安徽贝克制药股份有限公司 2025-03-14 CN disclosed
CN-116354845-B Compound with function of resisting Fusobacterium nucleatum and application thereof 中国人民解放军海军军医大学 2025-03-07 CN disclosed
CN-118221613-A Substituted piperazine compound and medical application thereof 中国人民解放军军事科学院军事医学研究院 2024-06-21 CN disclosed
US-4774360-A Converting enol ester precursor of a benzoyl-1,3-cycloalkyldione to a benzoyl-1,3-cycloalkyldione STAUFFER CHEMICAL COMPANY (US) 1988-09-27 US disclosed
CN-87106999-A 2-(2-substituted benzoyl)-4-(replacement)-1, the 3-cyclohexanedione 1988-09-21 CN disclosed
EP-0278742-A2 Cyclic diones MAY & BAKER LIMITED (GB) 1988-08-17 EP disclosed
EP-0264859-A2 2-(2-substituted benzoyl)-4-(substituted)-1,3-cyclohexanediones, a process for their production and a herbicidal composition containing them STAUFFER CHEMICAL COMPANY (US) 1988-04-27 EP disclosed
EP-0213892-A2 Herbicidally active enols ROHM AND HAAS COMPANY (US) 1987-03-11 EP disclosed
US-3971741-A DISPERSION PIGMENTS BAYER AKTIENGESELLSCHAFT (DT) 1976-07-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250282960-A1 PAINT THINNER FORMULATION ARNT, AHR, BCOR HPD 319/4885FLT1 3955/4885FLT4 3742/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.