Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERBB2 | P04626 | 1/20 | 0.58 |
| ▸ | MAOA | P21397 | 3/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28436924 | 0.78 | ERBB2 (0.54) | ERBB2MAOAMAOBMEN1MAPT | |
| SCHEMBL49620 | 0.73 | ERBB2 (1.00) | ERBB2MAOAMAOBMEN1MAPT | |
| SCHEMBL8582723 | 0.71 | ERBB2 (0.50) | ERBB2MAOAMAOBMEN1MAPT | |
| SCHEMBL28113764 | 0.70 | ERBB2 (0.91) | ERBB2MAOAMAOBMEN1MAPT | |
| SCHEMBL1957619 | 0.69 | ERBB2 (0.58) | ERBB2MAOAMAOBMEN1MAPT | |
| SCHEMBL1067701 | 0.69 | ERBB2 (0.58) | ERBB2MAOAMAOBMEN1MAPT | |
| SCHEMBL27645404 | 0.69 | ERBB2 (0.58) | ERBB2MAOAMAOBMEN1MAPT | |
| SCHEMBL28861798 | 0.69 | ERBB2 (0.58) | ERBB2MAOAMAOBMEN1MAPT | |
| SCHEMBL1524084 | 0.68 | ERBB2 (0.58) | ERBB2MAOAMAOBMEN1MAPT | |
| SCHEMBL8582510 | 0.68 | ERBB2 (0.58) | ERBB2MAOAMAOBMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118026994-A | Chiral resolution method of R- (+) -lipoic acid | 南京桦冠生物技术有限公司 | 2024-05-14 | — | — | CN | disclosed |
| US-10744146-B2 | Composition having effects of preventing or ameliorating conditions or diseases caused by brain hypofunction | SUNTORY HOLDINGS LIMITED (JP) | 2020-08-18 | — | — | US | disclosed |
| EP-1419768-B1 | COMPOSITIONS HAVING EFFECTS OF PREVENTING OR AMELIORATING CONDITIONS OR DISEASES CAUSED BY BRAIN HYPOFUNCTION | SUNTORY HOLDINGS LTD (JP) | 2011-08-17 | — | — | EP | disclosed |
| US-20040266874-A1 | Composition having effects of preventing or ameliorating conditions or diseases caused by brain hypofunction | SUNTORY HOLDINGS LIMITED (JP) | 2004-12-30 | — | — | US | disclosed |
| EP-1419768-A1 | COMPOSITIONS HAVING EFFECTS OF PREVENTING OR AMELIORATING CONDITIONS OR DISEASES CAUSED BY BRAIN HYPOFUNCTION | SUNTORY LIMITED (JP) | 2004-05-19 | — | — | EP | disclosed |
| EP-0729753-B1 | Use of dioxabicyclo[3.3.0]actanes for treatment and prevention of cerebral apoplexy | SUNTORY LTD (JP) | 2000-05-10 | — | — | EP | disclosed |
| US-5889046-A | ADMINISTERING DIOXABICYLCO(3,3,0)OCTANE DERIVATIVE TO THE PATIENT SUFFERING FROM HYPERTENSION OR MEDICAL SYMPTOMS CAUSED BY IT | SUNTORY LIMITED (JP) | 1999-03-30 | — | — | US | disclosed |
| EP-0729753-A1 | Agents for treatment or prevention of hypertension and related symptons and disorders; their preparation and use | SUNTORY LIMITED (JP) | 1996-09-04 | — | — | EP | disclosed |