Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERBB2 | P04626 | 1/20 | 0.58 |
| ▸ | MAOA | P21397 | 5/20 | 0.44 |
| ▸ | MAOB | P27338 | 5/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1957619 | 0.74 | ERBB2 (0.58) | ERBB2MAOAMAOBTDP1MEN1 | |
| SCHEMBL49620 | 0.74 | ERBB2 (1.00) | ERBB2MAOAMAOBTDP1MEN1 | |
| SCHEMBL27645404 | 0.74 | ERBB2 (0.58) | ERBB2MAOAMAOBTDP1MEN1 | |
| SCHEMBL28861798 | 0.74 | ERBB2 (0.58) | ERBB2MAOAMAOBTDP1MEN1 | |
| SCHEMBL8582510 | 0.73 | ERBB2 (0.58) | ERBB2MAOAMAOBTDP1MEN1 | |
| SCHEMBL8582723 | 0.72 | ERBB2 (0.50) | ERBB2MAOAMAOBTDP1MEN1 | |
| SCHEMBL20087538 | 0.72 | MAOA (0.57) | ERBB2MAOAMAOBTDP1MEN1 | |
| SCHEMBL28113764 | 0.70 | ERBB2 (0.91) | ERBB2MAOAMAOBTDP1MEN1 | |
| SCHEMBL899103 | 0.70 | ERBB2 (0.54) | ERBB2MAOAMAOBTDP1MEN1 | |
| SCHEMBL1524084 | 0.69 | ERBB2 (0.58) | ERBB2MAOAMAOBTDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130011495-A1 | ANTIFUNGAL COMPOUNDS AND USE THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE-CNRS- (FR) | 2013-01-10 | — | — | US | disclosed |
| EP-2453745-A2 | ANTIFUNGAL COMPOUNDS AND USE THEREOF | Centre National de la Recherche Scientifique (FR) | 2012-05-23 | — | — | EP | disclosed |
| WO-2011007104-A2 | ANTIFUNGAL COMPOUNDS AND USE THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2011-01-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130011495-A1 | ANTIFUNGAL COMPOUNDS AND USE THEREOF | SCLY, SUCLG1, ACSL3 | ERBB2 3379/4885MAOA 778/4885MAOB 1191/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.