SCHEMBL28113764

SCHEMBL28113764

COC1=CC(=O)C=CC1=O.O=[Fe]

nearest known ligand 0.91

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERBB2 P04626 1/20 0.91
MEN1 O00255 4/20 0.52
MAPT P10636 4/20 0.52
KMT2A Q03164 4/20 0.52
KDM4E B2RXH2 3/20 0.52
MAPK1 P28482 2/20 0.52
HKDC1 Q2TB90 2/20 0.52
TP53 P04637 2/20 0.52
CYP3A4 P08684 2/20 0.52
USP2 O75604 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
TDP1 Q9NUW8 2/20 0.44
PKM P14618 1/20 0.44
MCL1 Q07820 1/20 0.44
ALOX5 P09917 7/20 0.43
PTGS2 P35354 6/20 0.43
MAOA P21397 1/20 0.41
MAOB P27338 1/20 0.41
SETD7 Q8WTS6 1/20 0.38
ALDH1A1 P00352 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL49620 0.95 ERBB2 (1.00) ERBB2MEN1MAPTKMT2AKDM4E
SCHEMBL21887167 0.78 ERBB2 (0.70) ERBB2MEN1MAPTKMT2AKDM4E
SCHEMBL13302687 0.74 ERBB2 (0.64) ERBB2MEN1MAPTKMT2AKDM4E
SCHEMBL5214897 0.74 ERBB2 (0.64) ERBB2MEN1MAPTKMT2AKDM4E
SCHEMBL49737 0.73 ERBB2 (0.62) ERBB2MEN1MAPTKMT2AKDM4E
SCHEMBL11745039 0.73 ERBB2 (0.62) ERBB2MEN1MAPTKMT2AKDM4E
SCHEMBL12253389 0.71 ERBB2 (0.60) ERBB2MEN1MAPTKMT2AKDM4E
SCHEMBL11484215 0.71 ERBB2 (0.59) ERBB2MEN1MAPTKMT2AKDM4E
SCHEMBL28856262 0.71 ERBB2 (0.59) ERBB2MEN1MAPTKMT2AKDM4E
SCHEMBL28259188 0.71 ERBB2 (0.59) ERBB2MEN1MAPTKMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106083558-A The method separating anti-tumor active ingredient from Fructus Tritici aestivi fermented product 江南大学 2016-11-09 CN disclosed