Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.56 |
| ▸ | APP | P05067 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 7/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.43 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | HTT | P42858 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | THRB | P10828 | 4/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | VDR | P11473 | 5/20 | 0.43 |
| ▸ | MMP14 | P50281 | 1/20 | 0.41 |
| ▸ | ALPG | P10696 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.37 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2401411 | 1.00 | MAPT (0.56) | MAPTAPPMEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL29363133 | 1.00 | MAPT (0.56) | MAPTAPPMEN1KMT2ALMNA | |
| SCHEMBL13043718 | 0.99 | MAPT (0.57) | MAPTAPPMEN1KMT2ALMNA | |
| SCHEMBL13235724 | 0.88 | MAPT (0.58) | MAPTAPPMEN1KMT2ALMNA | |
| SCHEMBL13043721 | 0.87 | MAPT (0.54) | MAPTAPPMEN1KMT2ALMNA | |
| SCHEMBL13908712 | 0.86 | MAPT (0.53) | MAPTAPPMEN1KMT2ALMNA | |
| SCHEMBL13069889 | 0.86 | MAPT (0.57) | MAPTAPPMEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL29370641 | 0.86 | MAPT (0.50) | MAPTAPPMEN1KMT2ALMNA | |
| SCHEMBL16997443 | 0.85 | MAPT (0.55) | MAPTAPPMEN1KMT2ALMNA | |
| SCHEMBL14159484 | 0.85 | MAPT (0.58) | MAPTAPPMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2356182-B1 | RADIATION CURABLE COATING MATERIALS | BASF SE (DE) | 2015-05-06 | — | — | EP | disclosed |
| US-20130299736-A1 | RADIATION-CURABLE COATING MATERIALS | BASE SE (DE) | 2013-11-14 | — | — | US | disclosed |
| US-20110230617-A1 | RADIATION-CURABLE COATING MATERIALS | BASF SE (DE) | 2011-09-22 | — | — | US | disclosed |
| EP-2356182-A1 | RADIATION CURABLE COATING MATERIALS | BASF SE (DE) | 2011-08-17 | — | — | EP | disclosed |
| WO-2010055050-A1 | RADIATION CURABLE COATING MATERIALS | BASF SE (DE) | 2010-05-20 | — | — | WO | disclosed |
| US-20050152994-A1 | Composition and process for coloring and preserving wood | OSMOSE, INC. | 2005-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110230617-A1 | RADIATION-CURABLE COATING MATERIALS | RAD51, MGMT, RAD54L | MAPT 34/4885APP 2675/4885MEN1 514/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.