SCHEMBL2324082

SCHEMBL2324082

CCOC1=CC2=CC[C@@H]3[C@H](CC[C@]4(CC)C(=O)C=C[C@@H]34)[C@H]2CC1

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 1/20 0.35
AR P10275 2/20 0.32
NR3C2 P08235 1/20 0.32
PGR P06401 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2320541 0.92 SRD5A2 (0.36) SRD5A2ARNR3C2PGR
SCHEMBL9007396 0.92 SRD5A2 (0.36) SRD5A2ARNR3C2PGR
SCHEMBL12446650 0.84 SRD5A2 (0.39) SRD5A2ARNR3C2PGR
SCHEMBL6841928 0.81 SRD5A2 (0.47) SRD5A2
SCHEMBL6841929 0.81 SRD5A2 (0.47) SRD5A2
SCHEMBL16337497 0.78 SRD5A2 (0.38) SRD5A2
SCHEMBL2337193 0.77 SRD5A2 (0.36) SRD5A2
SCHEMBL15079264 0.74 SRD5A2 (0.63) SRD5A2
SCHEMBL6379452 0.74 SRD5A2 (0.63) SRD5A2
SCHEMBL17591557 0.74 SRD5A2 (0.63) SRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9012667-B2 Process for introducing a double bond into position 15, 16 of a steroid LABORATOIRE THERAMEX (MC) 2015-04-21 US disclosed
EP-2534165-B1 A PROCESS FOR INTRODUCING A DOUBLE BOND INTO POSITION 15,16 OF A STEROID THERAMEX (MC) 2013-07-24 EP disclosed
US-20130137885-A1 PROCESS FOR INTRODUCING A DOUBLE BOND INTO POSITION 15, 16 OF A STEROID LABORATOIRE THERAMEX (MC) 2013-05-30 US disclosed
EP-2534165-A2 A PROCESS FOR INTRODUCING A DOUBLE BOND INTO POSITION 15,16 OF A STEROID Laboratoire Theramex (MC) 2012-12-19 EP disclosed
WO-2011098439-A2 A PROCESS FOR INTRODUCING A DOUBLE BOND INTO POSITION 15,16 OF A STEROID LABORATOIRE THERAMEX (MC) 2011-08-18 WO disclosed
EP-2354150-A1 Process for the preparation of gestodene LABORATOIRE THERAMEX (MC) 2011-08-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130137885-A1 PROCESS FOR INTRODUCING A DOUBLE BOND INTO POSITION 15, 16 OF A STEROID CYP17A1, NR5A1, HSD17B7 SRD5A2 8/4885AR 89/4885NR3C2 15/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.