SCHEMBL15079264

SCHEMBL15079264

CCOC1=CC2=CC[C@@H]3C(CC[C@]4(C)C(=O)CCC34)[C@H]2CC1

nearest known ligand 0.63

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 1/20 0.63
CYP19A1 P11511 19/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17591557 1.00 SRD5A2 (0.63) SRD5A2CYP19A1
SCHEMBL6379452 1.00 SRD5A2 (0.63) SRD5A2CYP19A1
SCHEMBL17831186 1.00 SRD5A2 (0.63) SRD5A2CYP19A1
SCHEMBL9226232 0.89 SRD5A2 (0.68) SRD5A2CYP19A1
SCHEMBL9226234 0.89 SRD5A2 (0.68) SRD5A2CYP19A1
SCHEMBL6841928 0.87 SRD5A2 (0.47) SRD5A2CYP19A1
SCHEMBL6841929 0.87 SRD5A2 (0.47) SRD5A2CYP19A1
SCHEMBL17831184 0.85 SRD5A2 (0.45) SRD5A2CYP19A1
SCHEMBL2909333 0.84 SRD5A2 (0.69) SRD5A2CYP19A1
SCHEMBL21140787 0.84 SRD5A2 (0.69) SRD5A2CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9296780-B2 Process for alkynylating 16-substituted-17-keto steroids CRYSTAL PHARMA, S.A.U. (ES) 2016-03-29 US disclosed
US-20150005518-A1 PROCESS FOR ALKYNYLATING 16-SUBSTITUTED-17-KETO STEROIDS CRYSTAL PHARMA, S.A.U. (ES) 2015-01-01 US disclosed
WO-2013092668-A1 PROCESS FOR ALKYNYLATING 16-SUBSTITUTED-17-KETO STEROIDS CRYSTAL PHARMA, S.A.U. (ES) 2013-06-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150005518-A1 PROCESS FOR ALKYNYLATING 16-SUBSTITUTED-17-KETO STEROIDS HSD17B7, NR3C2, CYP17A1 SRD5A2 75/4885CYP19A1 49/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.