Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HRH2 | P25021 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4441606 | 0.88 | LMNA (0.56) | LMNAPOLBSMN1; SMN2GAAATM | |
| SCHEMBL30473383 | 0.86 | LMNA (0.55) | LMNAPOLBSMN1; SMN2GAAATM | |
| SCHEMBL4631015 | 0.85 | GAA (0.59) | POLBSMN1; SMN2GAAATMTHRB | |
| SCHEMBL7449135 | 0.83 | POLB (0.63) | LMNAPOLBSMN1; SMN2GAAATM | |
| SCHEMBL184778 | 0.82 | LMNA (0.61) | LMNAPOLBSMN1; SMN2GAAATM | |
| SCHEMBL7339506 | 0.82 | LMNA (0.61) | LMNAPOLBSMN1; SMN2GAAATM | |
| SCHEMBL4193322 | 0.82 | LMNA (0.54) | LMNAPOLBSMN1; SMN2GAAATM | |
| SCHEMBL9405372 | 0.81 | POLB (0.73) | LMNAPOLBSMN1; SMN2GAAATM | |
| SCHEMBL856302 | 0.81 | SMN1; SMN2 (0.59) | LMNAPOLBSMN1; SMN2GAAATM | |
| SCHEMBL5156110 | 0.81 | LMNA (0.59) | LMNAPOLBSMN1; SMN2GAAATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011094890-A1 | PHENYLALANINE DERIVATIVES AND THEIR USE AS NON-PEPTIDE GLP-1 RECEPTOR MODULATORS | ARGUSINA INC. (US) | 2011-08-11 | — | — | WO | disclosed |